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David W. Threadgill, PhD

University Distinguished Professor
Tom & Jean McMullin Chair in Genetics
Department of Molecular and Cellular Medicine
College of Medicine, Texas A&M Health Science Center
Department of Veterinary Pathobiology
College of Veterinary Medicine & Biomedical Sciences
Director, Institute for Genome Sciences & Society
Texas A&M University, College Station, Texas

Dr. Threadgill’s genetics research program uses the mouse as an experimental model to investigate factors that contribute to inter-individual differences in maintenance of health and incidence of disease in both animals and humans. Current research activities include the identification and functional characterization of alleles contributing to cancer susceptibility, the function of the Erbb gene family in development and disease, and the role of genetic variation in response to environmental stimuli, toxicants, or stressors. To facilitate these investigations, his team develops genetic tools to understand the complex genetic and environmental etiologies that result in disease phenotypes. Dr. Threadgill received his BS in Zoology (1983) and PhD in Genetics (1989), under the mentorship of Dr. James Womack, from Texas A&M University. Following an NIH-funded Postdoctoral Fellowship at Case Western Reserve University in Dr. Terry Magnuson’s laboratory, he became an Assistant Professor in the Department of Cell Biology at Vanderbilt University in 1996. In 2000, he moved to the University of North Carolina at Chapel Hill where he was promoted to Professor in the Department of Genetics. In 2008, he moved to North Carolina State University as Professor and Head of the Department of Genetics. In 2011 Dr. Threadgill was named a Fellow in the American Association for the Advancement of Science in recognition of his distinguished contributions to the field of genetics, particularly for envisioning the Collaborative Cross model and establishing a new paradigm for pre-clinical drug safety testing. In 2013, Dr. Threadgill joined the faculty at Texas A&M University where he is the Director of the Texas A&M Institute for Genome Sciences & Society.